Video from Professor G - Pharmacology on YouTube

Construct a Schild plot, determine pA₂ and interpret a slope of unity as evidence of simple competitive antagonism.

Why this video

It walks through how to calculate dose ratios, plot the Schild regression, determine the pA₂ from the intercept, and interpret the slope for competitive antagonism.

Heads up

The video plots log(r - 1) against log[antagonist] (where the x-intercept is -pA₂), whereas this course plots against -log[B] so the x-intercept directly equals pA₂.

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