Ki vs IC50: Antagonists, Cheng–Prusoff, Binding Affinity and Potency

Video from Professor G - Pharmacology on YouTube

Describe competition binding experiments (IC₅₀) and the conversion of IC₅₀ to Ki (Cheng–Prusoff relationship).

Name: Ki vs IC50: Antagonists, Cheng–Prusoff, Binding Affinity and Potency
Uploaded: 2026-04-20T12:01:40Z
Duration: 15 min 42 s
Description: This video clearly explains the distinction between IC₅₀ and Kᵢ and demonstrates how to convert between them using the Cheng–Prusoff relationship alongside its assumptions and limitations.

PHM 309 Introduction to Pharmacology

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This video clearly explains the distinction between IC₅₀ and Kᵢ and demonstrates how to convert between them using the Cheng–Prusoff relationship alongside its assumptions and limitations.

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