Video from Ninja Nerd on YouTube

Describe phase I (oxidation, reduction, hydrolysis) and phase II (glucuronidation, sulfation, acetylation, glutathione conjugation, methylation) reactions and the properties of their products.

Why this video

It systematically walks through the mechanisms of both Phase I and Phase II drug biotransformations, explaining how functionalisation and conjugation reactions alter drug molecules.

Heads up

It covers clinical factors and practice problems affecting metabolism that go beyond the basic reaction types and product properties asked for by the objective.

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