Video from Anant`s Pharmacology on YouTube

Explain receptor up-regulation and supersensitivity (e.g. rebound after abrupt β-blocker withdrawal) and their clinical implications.

Why this video

It explains the mechanisms of receptor up-regulation and supersensitivity caused by agonist deprivation, directly citing the clinical consequences of abrupt propranolol discontinuation.

Heads up

It also covers receptor down-regulation and desensitisation, which are outside this specific objective.

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