Video from Ninja Nerd on YouTube

2.4.2 Explain the regulation of fatty acid synthesis and its reciprocal relation to beta-oxidation (malonyl-CoA).

Why this video

It explains the allosteric and hormonal regulation of acetyl-CoA carboxylase alongside how malonyl-CoA reciprocally inhibits beta-oxidation by blocking carnitine palmitoyltransferase I (CPT-I).

Heads up

Check whether glucagon-mediated inactivation of ACC is presented as direct phosphorylation by PKA rather than indirect regulation through inhibitor-1 and AMPK.

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