GEMP - Analytical and Biological Variables
Chemical Pathology on Analytical and Biological Variables Introduction Chemical pathology, a branch of laboratory medicine, focuses on the biochemical basis of disease and plays a crucial role in diagnosis and management. Understanding analytical and biological variables is essential as it affects the interpretation of laboratory results, impacting patient care and clinical decision-making....
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Question 1
Which factor is considered an analytical variable that affects laboratory test results?
Explanation
Specimen handling and preparation are critical analytical variables that impact the reliability of laboratory results, ensuring accurate diagnostics.
Question 2
Which of the following is an example of exogenous interference in laboratory tests?
Explanation
Exogenous interference refers to external substances, such as medications or dietary supplements, that can impact the accuracy of test results.
Question 3
Which biological variable is important to consider when interpreting thyroid hormone tests?
Explanation
The physiological state of the patient, such as pregnancy or illness, can significantly affect thyroid hormone levels, making it essential for accurate interpretation.
Question 4
Diurnal variation primarily affects the interpretation of which type of analytes?
Explanation
Diurnal variation refers to the natural fluctuations of hormone levels throughout the day, critically affecting the accuracy of hormone tests.
Question 5
Calibrating laboratory instruments primarily ensures what?
Explanation
Regular calibration of laboratory instruments is essential to maintain the precision and reliability of test results, which is vital for accurate diagnosis.
Question 6
What can commonly cause turbidity in serum samples, impacting glucose readings?
Explanation
Lipemia, which refers to high levels of lipids in the blood, can cause turbidity and interfere with various laboratory test readings, including glucose.
Question 7
In calcium testing, what other biochemical component must often be adjusted for accurate results?
Explanation
When assessing serum calcium, it is crucial to account for albumin levels since calcium binds to this protein, influencing the accurate assessment of calcium status.