GEMP - Action Potential 🔥
Action Potential
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Time limit: 4 minutes
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Multiple attempts are not allowed
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All questions must be answered to submit
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Question 1
A researcher is studying a newly identified type of neuron that requires a membrane potential of -55 mV to initiate action potentials. If the neuron is consistently activated by a sub-threshold stimulus, what physiological significance does this have on the frequency of action potentials?
Explanation
The neuron can respond to stronger stimuli by increasing its firing frequency, but a sub-threshold stimulus cannot trigger action potentials.
Question 2
During an experiment, it was observed that after a neuron depolarizes, the membrane potential returns to its resting state. Which mechanism is primarily responsible for this repolarization phase?
Explanation
Repolarization occurs via the opening of potassium channels that allow K⁺ ions to exit, restoring the negative membrane potential.
Question 3
Consider a scenario where a patient has a damaged refractory period due to a neurological condition. What potential cardiovascular implication could arise from this dysfunction?
Explanation
A damaged refractory period may lead to inappropriate timing of action potentials, which can cause arrhythmias.
Question 4
How does the all-or-nothing principle of action potentials relate to the concept of stimulus intensity in the context of neuronal coding for sensory input?
Explanation
Stimulus intensity is encoded by the frequency of action potentials, not by their amplitude, aligning with the all-or-nothing principle.
Question 5
In a study, researchers observed that in skeletal muscle cells, action potentials are critical for muscle contraction. If a drug inhibits the release of calcium ions from the sarcoplasmic reticulum, what is the expected outcome regarding muscle contraction?
Explanation
Calcium ions are essential for muscle contraction; inhibition of their release would result in inadequate muscle contraction.
Question 6
If a scientist varies the sodium concentration outside a neuron while maintaining all other conditions constant, what effect would this have on the resting membrane potential, and how would it influence the threshold potential?
Explanation
Lowering sodium concentration outside the neuron makes it harder to depolarize, thus requiring a greater threshold potential to generate an action potential.
Question 7
Analyzing the process of depolarization, which factor is essential for the rapid change observed during action potential initiation in neurons?
Explanation
Depolarization is primarily characterized by the quick influx of sodium ions when sodium channels open after reaching threshold potential.
Question 8
In a clinical scenario, a patient is experiencing frequent muscle spasms. What could be the physiological reason behind the condition if the patient has an elevated frequency of action potentials in motor neurons?
Explanation
An elevated frequency of action potentials can lead to an increased release of neurotransmitters, causing sustained contraction and spasms.
Question 9
Considering the misconception around 'all-or-nothing' responses in action potentials, how might the frequency of action potentials influence neural encoding of specific stimuli?
Explanation
The frequency of action potentials is instrumental in signaling to the brain the intensity of the stimulus received, aligning with neural coding principles.