GEMP - Cell injury
Reversible and Irreversible Cell Injury Introduction Cell injury is a critical concept in medical pathology that describes the responses of cells to various stimuli and stresses. Understanding the differences between reversible and irreversible cell injury is fundamental for diagnosing diseases and guiding treatment strategies, as the fate of a cell often determines the health and function of...
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Question 1
In which scenario would cell injury be classified as irreversible?
Explanation
Prolonged ischemia resulting in cell death, such as myocardial necrosis, indicates irreversible cell injury.
Question 2
What characterizes reversible cell injury?
Explanation
Reversible cell injury allows cells to recover their structure and function once the stressor is removed.
Question 3
Which of the following is a mechanism of irreversible cell injury?
Explanation
Irreversible cell injury commonly involves mitochondrial dysfunction, leading to loss of ATP production.
Question 4
What is a common morphological change associated with reversible cell injury?
Explanation
Reversible cell injury can lead to cellular swelling and fatty changes, which can be reversed.
Question 5
Which following factor is least likely to cause irreversible cell injury?
Explanation
Mild stress that allows for cell recovery does not typically lead to irreversible injury.
Question 6
What is the significance of recognizing reperfusion injury?
Explanation
Reperfusion injury can occur when blood supply returns, potentially exacerbating cell injury through oxidative stress.
Question 7
Which condition exemplifies a reversible cell injury due to toxic substance exposure?
Explanation
Fatty liver resulting from acute alcohol consumption is an example of reversible cell injury.
Question 8
Which statement regarding apoptosis and necrosis is true?
Explanation
Apoptosis and necrosis have distinct characteristics that differentiate these forms of cell death.
Question 9
Which of the following factors is critical in determining the fate of a cell after injury?
Explanation
The nature and duration of the stressor play a vital role in determining whether cell injury is reversible or irreversible.
Question 10
Which cell type may recover from mild stress through adaptive mechanisms?
Explanation
Neurons may recover from mild stress through adaptive mechanisms, but severe stress can lead to apoptosis.