GEMP - Morphologic Patterns of Acute Inflammation
Introduction Acute inflammation is a vital response of the body to injury or infection characterized by a rapid onset of vascular and cellular changes. Understanding the morphologic patterns of acute inflammation is essential for medical professionals as it aids in diagnosing underlying pathologies and developing appropriate therapeutic strategies. Key Concepts 1. Vascular Changes Acute inf...
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Question 1
What is the first step in the vascular changes associated with acute inflammation?
Explanation
Acute inflammation begins with transient vasoconstriction, followed by vasodilation which leads to increased blood flow.
Question 2
Which of the following is the primary leukocyte involved in the cellular response of acute inflammation?
Explanation
Neutrophils are the primary leukocytes that migrate to the site of injury during acute inflammation.
Question 3
Which process involves the adhesion of neutrophils to the blood vessel endothelium during acute inflammation?
Explanation
Margination refers to the process where neutrophils adhere to the endothelium of blood vessels.
Question 4
What type of exudate is characterized by a clear, yellowish fluid?
Explanation
Serous exudate is a clear, yellowish fluid that typically results from mild inflammation.
Question 5
Which morphologic pattern of inflammation is characterized by the production of pus?
Explanation
Suppurative inflammation is marked by the formation of pus, typically due to bacterial infections.
Question 6
What type of inflammation involves significant fibrin deposition and can be seen in conditions such as rheumatic fever?
Explanation
Fibrinous inflammation is characterized by fibrin deposition, often observed in bacterial infections and conditions like rheumatic fever.
Question 7
In acute appendicitis, which type of inflammation is typically observed around the appendiceal wall?
Explanation
Acute appendicitis typically involves neutrophilic infiltration and possibly leads to suppurative inflammation.
Question 8
What ultimately occurs during the resolution of acute inflammation?
Explanation
During the resolution phase of inflammation, phagocytosis of cellular debris by macrophages is crucial for healing.
Question 9
Which of the following substances is NOT a chemical mediator involved in increasing blood vessel permeability during acute inflammation?
Explanation
While prostaglandins play various roles in inflammation, they are not primarily known for increasing blood vessel permeability compared to histamine and nitric oxide.
Question 10
Which misconception about inflammation is commonly held?
Explanation
A common misconception is that inflammation is inherently harmful; however, it is a necessary process for initiating repair and combating infections.
Question 11
What is the role of chemotaxis during the acute inflammatory response?
Explanation
Chemotaxis describes the movement of neutrophils toward chemical signals released by damaged tissues or pathogens.
Question 12
After resolution of inflammation, which process is crucial for restoring tissue integrity?
Explanation
Restoration of tissue architecture involves growth factors and cytokines that aid in healing after inflammation resolves.
Question 13
Which inflammatory response is characterized by tissue necrosis due to severe damage?
Explanation
Necrotizing inflammation is characterized by tissue necrosis resulting from severe damage, often from aggressive infections.