GEMP - Systemic Effects of Inflammation
Introduction Inflammation is a complex biological response to injury, infection, or harmful stimuli. It serves as a protective mechanism, facilitating healing and defense against pathogens. Understanding the systemic effects of inflammation is essential in the medical field, as it plays a pivotal role in various diseases, including autoimmune disorders, chronic infections, and cancer. Key Co...
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Time limit: 7 minutes
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Question 1
Multiple choiceWhat characterizes acute inflammation?
Explanation
Acute inflammation is characterized by a rapid response to injury or infection, usually lasting from hours to days.
Question 2
Multiple choiceWhat role do pro-inflammatory cytokines like IL-1 and TNF-alpha play in inflammation?
Explanation
Pro-inflammatory cytokines such as IL-1 and TNF-alpha are released during inflammation to activate immune cells and promote inflammatory responses.
Question 3
Multiple choiceWhich of the following is NOT a systemic manifestation of inflammation?
Explanation
Localized redness is a hallmark of the localized response in inflammation and is not systemic.
Question 4
Multiple choiceWhich condition is characterized by chronic inflammation of the synovial joints?
Explanation
Rheumatoid arthritis is an autoimmune disease marked by chronic inflammation affecting the synovial joints.
Question 5
Multiple choiceWhat is the function of C-reactive protein (CRP) in the context of inflammation?
Explanation
C-reactive protein (CRP) is produced by the liver as part of the acute phase response and serves as a biomarker for inflammation.
Question 6
Multiple choiceWhich type of inflammation can lead to tissue damage if it persists?
Explanation
Chronic inflammation can result in ongoing tissue damage, contributing to various diseases.
Question 7
Multiple choiceWhat term describes the hyper-inflammatory response observed in severe COVID-19 cases?
Explanation
The term 'cytokine storm' refers to a severe hyper-inflammatory response that can occur in serious cases of COVID-19.
Question 8
Multiple choiceHow is the resolution phase of inflammation characterized?
Explanation
The resolution phase of inflammation involves the active clearance of immune cells and apoptotic cells, signaling the end of the inflammatory response.
Question 9
Multiple choiceWhich immune cells primarily recognize harmful agents to initiate inflammation?
Explanation
Immune cells with pattern recognition receptors (PRRs) recognize harmful agents and initiate the inflammatory process.
Question 10
Multiple choiceWhat type of pattern does atherosclerosis reflect in relation to inflammation?
Explanation
Atherosclerosis is linked to chronic inflammation, which can lead to the instability of plaques.
Question 11
Multiple choiceIn the context of inflammation, which cytokine is primarily responsible for inducing fever?
Explanation
Interleukin-1 (IL-1) is a key cytokine involved in inducing fever during the inflammatory response.
Question 12
Multiple choiceWhat is the role of immune cells during the acute phase response?
Explanation
During the acute phase response, immune cells enhance the overall immune response to combat infection.
Question 13
Multiple choiceWhich disease is NOT linked to chronic inflammation?
Explanation
Acute bronchitis primarily involves an acute inflammatory response rather than chronic inflammation.
Question 14
Multiple choiceWhich of the following statements accurately describes chronic inflammation and its implications in disease processes?
Explanation
Chronic inflammation is a prolonged response that can lead to tissue damage and is a significant factor in the development of various diseases, including autoimmune disorders, cardiovascular diseases, and cancer.