INTRO TO IMMUNOLOGY
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Time limit: 50 minutes
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Question 1
What is the primary focus of immunology?
Explanation
Immunology is defined as the study of the immune system and immunity, which focuses on host defense against infection.
Question 2
What is the state of protection from infectious diseases called?
Explanation
Immunity refers to the state of protection against infectious diseases.
Question 3
Which of the following best describes innate immunity?
Explanation
Innate immunity is characterized by being non-specific and acting as the body's first line of defense against pathogens.
Question 4
What is the main characteristic of adaptive immunity?
Explanation
Adaptive immunity is specific for distinct antigens and develops memory, enabling a quicker response to previously encountered pathogens.
Question 5
Which component is NOT part of the innate immune response?
Explanation
Antibodies are part of the adaptive immune response, while mucus, neutrophils, and natural barriers like skin are components of the innate immune response.
Question 6
A patient exhibiting symptoms of an infection has a robust inflamed area characterized by heat, redness, pain, and loss of function. Which of the following statements best describes the underlying immune response occurring in this patient?
Explanation
The correct answer is that the inflammation is a result of innate immunity, as it represents the body’s immediate and non-specific response to the injury or invasion. The other options misinterpret the role and timing of adaptive immunity in the immune response, where memory and specificity primarily come into play after a first exposure.
Question 7
After a successful vaccination, which immune mechanism is attributed to the faster and more vigorous response during a subsequent exposure to the same pathogen?
Explanation
The correct choice reflects that the memory cells from the adaptive immune system are responsible for the accelerated and intensified immune response during subsequent exposures. The other options wrongly attribute the response to innate immunity or acute phase reactants, which do not provide a faster response based on prior exposure.
Question 8
[Case Scenario] A researcher is studying the immune system and its responses to infections. She observes that the body has both innate and adaptive immune responses. In her findings, she notes that the innate immune response activates immediately upon infection and includes physical and biochemical barriers that do not improve with repeated exposures. Conversely, the adaptive immune response takes time to fully activate but offers a long-lasting specific response that improves with subsequent exposures to the same pathogen. Question: Based on her observations, which statement correctly describes the primary differences between innate and adaptive immunity?
Explanation
The researcher highlighted the essential differences between innate and adaptive immunity—innate immunity's immediate and non-specific reactions and adaptive immunity's slower, specific, and memory-driven responses.
Question 9
[Case Scenario] In a laboratory, a team of scientists is evaluating how well various components of innate immunity respond to an infection. They focus specifically on the role of neutrophils and macrophages in phagocytosis and the release of inflammatory mediators like histamine. They also examine how these components function to prevent pathogen proliferation, as well as the role of structural barriers like skin and mucus in blocking pathogen entry. Question: Based on their observations of the innate immune response, which statement best describes its overall function and mechanisms during the initial stages of infection?
Explanation
This scenario illustrates how the innate immune system functions as a first line of defense, utilizing both physical barriers and cellular responses to respond immediately to infections.
Question 10
[Case Scenario] During an immunology seminar, a speaker discusses the complement system's pathways in adaptive immunity, including the classical, lectin, and alternative pathways. He explains how these pathways interact and the importance of antibodies and other factors in enhancing phagocytosis and inflammation. The students notice that while the classical pathway requires the presence of antibodies, the alternative pathway does not, allowing for a continuous low-level activation. Question: Given the speaker's discussion on the complement system, which conclusion best encapsulates its role in the immune response?
Explanation
The seminar revealed how the complement system functions in both innate and adaptive immunity through varied pathways, particularly highlighting the classical pathway's reliance on antibodies for effective activation and subsequent immune response enhancement.